Fig. 8: Scheme of NSUN2 in DOX-induced myocardial injury.
From: NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress
NSUN2 promote the methylation modification of Nrf2 mRNA, and increase the level of Nrf2 protein, which activates the downstream antioxidant stress response and reduces the damage caused by ROS.
