Fig. 1: Identification of circTRPS1-2 through high-throughput sequencing of ESCC tissues. | Cell Death Discovery

Fig. 1: Identification of circTRPS1-2 through high-throughput sequencing of ESCC tissues.

From: Circular RNA circTRPS1-2 inhibits the proliferation and migration of esophageal squamous cell carcinoma by reducing the production of ribosomes

Fig. 1: Identification of circTRPS1-2 through high-throughput sequencing of ESCC tissues.The alternative text for this image may have been generated using AI.

a Circos plot showing the chromosome positions of all circRNAs identified in ESCC tissues. b Differences in expression of circRNAs between ESCC and adjacent normal esophageal tissues. c Heatmap showing differences in expression of 41 circRNAs downregulated in ESCC tissues and 5 circRNAs upregulated in ESCC tissues. Differences are expressed as log (CPM) as calculated by EdgeR. d Volcano plot showing 10 circRNAs downregulated in ESCC tissues and 5 upregulated circRNAs. The circRNA hsa_circ_0085362 is marked. Grey indicates no significant difference; green, P ≥ 0.05 and | FC | ≥ 2; and red, P < 0.05 and | FC | ≥ 2, which served as the definition of differential circRNA expression. C or Cancer, ESCC tissue; CPM, counts per million; ESCC, esophageal squamous cell carcinoma; FC, fold change; N or Normal, adjacent normal esophageal tissue.

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