Fig. 3: Effects of IFN-γ on the formation of malignant ascites. | Cell Death Discovery

Fig. 3: Effects of IFN-γ on the formation of malignant ascites.

From: Interferon-γ secreted by recruited Th1 cells in peritoneal cavity inhibits the formation of malignant ascites

Fig. 3: Effects of IFN-γ on the formation of malignant ascites.The alt text for this image may have been generated using AI.

A The weight of peritoneal fluid at 14 days after intraperitoneal injection of H22 or S180 cells showed that deficiency of IFN-γ promoted the formation of peritoneal fluid in murine model of malignant ascites; B peritoneal permeability assay demonstrated IFN-γ deficiency increased peritoneal permeability through determining Evan’s blue; C the concentration of VEGF in peritoneal fluid and corresponding blood of WT or IFN-γ−/− mice with malignant ascites; left panel: H22; right panel: S180; D the concentration of angiotensin-2 in peritoneal fluid and corresponding blood of WT or IFN-γ−/− mice with malignant ascites; left panel: H22; right panel: S180. The difference between two groups was determined by t test. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001, ns no significant.

Back to article page