Fig. 4: Effects of IFN-γ on the growth of peritoneal carcinomatosis and the survival of mice. | Cell Death Discovery

Fig. 4: Effects of IFN-γ on the growth of peritoneal carcinomatosis and the survival of mice.

From: Interferon-γ secreted by recruited Th1 cells in peritoneal cavity inhibits the formation of malignant ascites

Fig. 4

A Representative photograph of WT and IFN-γ−/− mice after intraperitoneal injection of H22 and S180 cells. Marked abdomen expansion and multiple tumor foci were observed at 14 days after the administration of tumor cells. Representative photography showed most of tumor cells were found in visceral peritoneum; B positron emission tomography and computed tomography imaging of WT and IFN-γ−/− mice with malignant ascites; C total lesion glycolysis (TLG) on PET/CT of WT and IFN-γ−/− mice with malignant ascites. The difference between two groups was determined by t test; D survival curve of WT and IFN-γ−/− mice with malignant ascites. The difference between two groups was determined by pairwise log-rank tests; *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ns no significant.

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