Fig. 3: Differentially expressed genes and proteins of MOLM-13 and MOLM-13/sor cells. | Cell Death Discovery

Fig. 3: Differentially expressed genes and proteins of MOLM-13 and MOLM-13/sor cells.

From: The GSK3β/Mcl-1 axis is regulated by both FLT3-ITD and Axl and determines the apoptosis induction abilities of FLT3-ITD inhibitors

Fig. 3

A Growth inhibition rate of MOLM-13 and MOLM-13/sor cells treated with sorafenib for 72 h. B Apoptosis of MOLM-13 and MOLM-13/sor cells treated with sorafenib for 24 h as detected by AO-EB staining. C WES analysis showing FLT3 mutations in MOLM-13/sor cells. D Volcano plot of the differentially expressed genes in MOLM-13/sor cells compared to MOLM-13 cells. The green and red dots represent upregulated and downregulated genes, respectively. E KEGG classification of differentially expressed genes. The ordinate shows the KEGG pathway and the abscissa shows the number of genes under this pathway and its proportion in the total number of genes. F Differentially expressed proteins analyzed by Western blot analysis in MOLM-13 and MOLM-13/sor cells.

Back to article page