Fig. 1: Single-cell sequencing of normal pancreatic tissue and pancreatic cancer tissue, and TCGA database analysis. | Cell Death Discovery

Fig. 1: Single-cell sequencing of normal pancreatic tissue and pancreatic cancer tissue, and TCGA database analysis.

From: Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models

Fig. 1

a Flow chart of single cell sequencing. b Single cell sequencing of normal pancreas tissue, t-SNE analysis. c Single cell sequencing of tumor sample, t-SNE analysis. d, f ZDHHC5 expressing in normal pancreas tissue (heatmap and t-SNE analysis). e, g ZDHHC5 expressing in tumor sample (heatmap and t-SNE analysis). h TCGA public pancreatic cancer samples, the survival rate of ZDHHC5 (high expression, n = 45) patients and ZDHHC5 (low expression, n = 132) patients (upper) and the expression level of ZDHHC5 in pancreatic cancer patients (n = 178) or normal pancreas samples (n = 4).

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