Fig. 3: Molecular mechanisms of pyroptosis. | Cell Death Discovery

Fig. 3: Molecular mechanisms of pyroptosis.

From: Ferroptosis, pyroptosis and necroptosis in acute respiratory distress syndrome

Fig. 3

The mechanisms of pyroptosis are divided into canonical pathways mediated by caspase 1 and noncanonical pathways activated by caspase 4/5/11. LPS lipopolysaccharide, CARD recruitment domain, PRRs pattern recognition receptors, PYD pyrin domain, AIM melanoma, IL interleukin, GSDMD gasdermin D, NETs neutrophil extracellular traps, HMGB1 high-mobility group box 1.

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