Table 2 Correlation between clinicopathological features and TRIM3 expression (N = 348).

From: Dual roles of TRIM3 in colorectal cancer by retaining p53 in the cytoplasm to decrease its nuclear expression

 

N

TRIM3 expression

Negative(146)

Positive(202)

P

Age

   

0.533

 <50 years

20

6 (30.0%)

14 (70.0%)

 

 50–75 years

207

90 (43.5%)

117 (56.5%)

 

 >75 years

121

50 (41.3%)

71 (58.7%)

 

Sex

   

0.232

 Male

169

65 (38.5%)

104 (61.5%)

 

 Female

179

81 (45.3%)

98 (54.7%)

 

Tumor size

   

0.604

 <4 cm

115

52 (45.2%)

63 (54.8%)

 

 4–6 cm

175

69 (39.4%)

106 (60.6%)

 

 >6 cm

58

25 (43.1%)

33 (56.9%)

 

Tumor location

   

0.403

 Ascending

85

34 (40.0%)

51 (60.0%)

 

 Transverse

16

6 (37.5%)

10 (62.5%)

 

 Descending

30

17 (56.7%)

13 (43.3%)

 

 Sigmoid

91

41 (45.1%)

50 (54.9%)

 

 Rectum

126

48 (38.1%)

78 (61.9%)

 

T stage

   

0.172

 T1

19

9 (47.4%)

10 (52.6%)

 

 T2

51

28 (54.9%)

23 (45.1%)

 

 T3

198

80 (40.4%)

118 (59.6%)

 

 T4

80

29 (36.3%)

51 (63.8%)

 

N stage

   

0.920

 N0

224

96 (42.9%)

128 (57.1%)

 

 N1

84

34 (40.5%)

50 (59.5%)

 

 N2

40

16 (40.0%)

24 (60.0%)

 

M stage

   

0.010*

 M0

324

142 (43.8%)

182 (56.2%)

 

 M1

24

4 (16.7%)

20 (83.3%)

 

AJCC stage

   

0.026*

 I

60

31 (51.7%)

29 (48.3%)

 

 II

155

63 (40.6%)

92 (59.4%)

 

 III

109

48 (44.0%)

61 (56.0%)

 

 IV

24

4 (16.7%)

20 (83.3%)

 

Differentiation

   

0.619

 Well

124

50 (40.3%)

74 (59.7%)

 

 Moderate

206

90 (43.7%)

116 (56.3%)

 

 Poorly

18

6 (33.3%)

12 (66.7%)

 

P53

   

<0.001*

 Negative

136

79 (58.1%)

57 (41.9%)

 

 Positive

212

67 (31.6%)

145 (68.4%)

 
  1. P-value are based on chi-squared or Fisher’s exact test.
  2. *Significant difference.