Fig. 1: MYC in cells. | Cell Death Discovery

Fig. 1: MYC in cells.

From: The effects of MYC on tumor immunity and immunotherapy

Fig. 1

Activation of the WNT/β-catenin and MYC pathways can induce tumor cell proliferation and MYC can participate in immune cell-related activities to inhibit innate and adaptive immune responses. In addition, MYC can be activated by several cytokines secreted by CAFs, including IL-33 and chemokine, which leads to the suppression of tumor immunity.

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