Fig. 2: GATA4 promoted the differentiation of osteoblast in BMSCs. | Cell Death Discovery

Fig. 2: GATA4 promoted the differentiation of osteoblast in BMSCs.

From: GATA4-activated lncRNA MALAT1 promotes osteogenic differentiation through inhibiting NEDD4-mediated RUNX1 degradation

Fig. 2

A The transfection efficiency of shGATA4 and oeGATA4 in BMSCs was determined by qRT-PCR. B–F The relative expression of Runx1, ALP, OCN and OSX was evaluated after silencing or overexpressing GATA4. G The ALP activity was measured by a test kit. H Representative images of ALP staining. I The osteogenic calcification was analyzed by Alizarin Red staining. Mean ± SD, n = 3, *p < 0.05, **p < 0.01, ***p < 0.001. Statistical analysis was carried out by one-way ANOVA.

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