Fig. 5: METTL3/14/IGF2BP2-mediated proliferation of NSCLC stem cells upon GLI1 repression. | Cell Death Discovery

Fig. 5: METTL3/14/IGF2BP2-mediated proliferation of NSCLC stem cells upon GLI1 repression.

From: N6-methyladenine-mediated aberrant activation of the lncRNA SOX2OT-GLI1 loop promotes non-small-cell lung cancer stemness

Fig. 5: METTL3/14/IGF2BP2-mediated proliferation of NSCLC stem cells upon GLI1 repression.The alt text for this image may have been generated using AI.

A Proliferation assay of NSCLC cells transfected with METTL3/14/IGF2BP2 and/or GLI1 shRNA. B and C Spheroid formation assay and histogram of NSCLC cells transfected with METTL3/14/IGF2BP2 and/or GLI1 shRNA. D and E Clonal formation assay and histogram of NSCLC cells transfected with METTL3/14/IGF2BP2 and/or GLI1 shRNA. Magnification = ×100, scale bar = 200 μm.

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