Table 3 Application of ferroptosis-related miRNAs in tumor therapy.

From: Emerging roles of ferroptosis-related miRNAs in tumor metastasis

miRNA

Disposes

Cancer types

Expression levels in the sample

Models of evidence

References

miR-214

Prostate cancer

Downregulate

Clinical trials

[129]

miR-27a-3p

Prostate cancer

Upregulate

Clinical trials

[130]

miR-9

Nasopharyngeal carcinoma

Downregulate

Clinical trials

[131]

miR-17-92

Gastric cancer

Upregulate

Clinical trials

[132]

miR-375

Hepatocellular carcinoma

Downregulate

Clinical trials

[133]

miR-324-3p

Hepatocellular carcinoma

Downregulate

Clinical trials

[134]

miR-375

Colorectal carcinoma

Downregulate

Clinical trials

[135]

miR-137

Glioblastoma

Downregulate

Clinical trials

[136]

miR-324-3p

Icariside II

RCC

Upregulate

Cell culture

[108]

miR-214-3p

Ketamine

Liver cancer

Upregulate

Cell culture, animal models

[109]

miR-101-3p

Nanoparticle-coated

Lung cancer

Upregulate

Cell culture, animal models

[110]

miR-21-3p

Nanoparticle-coated

Melanoma

Upregulate

Cell culture, animal models

[137]

miR-744-5p

Propofol

NSCLC

Upregulate

Cell culture, animal models

[138]

  1. Some ferroptosis-related miRNAs have been proved to be diagnostic or prognostic biomarkers of cancer and can be used for targeted therapy.