Fig. 5: NRF2 activators induce mRNA expression of Caspase-4 in the human hepatic cell line. | Cell Death Discovery

Fig. 5: NRF2 activators induce mRNA expression of Caspase-4 in the human hepatic cell line.

From: NRF2 transcriptionally regulates Caspase-11 expression to activate HMGB1 release by Autophagy-deficient hepatocytes

Fig. 5

A, B Treatment with BM for 24 h induced Nqo1 (A), and Caspase-4 (B) expression in the human liver cancer cell line Huh7. C, D Treatment with tBHQ for 24 h induced Nqo1 (C), and Caspase-4 (D) expression in Huh7. mRNA expression levels were quantified by RT-PCR and normalized to that of β-actin. *P < 0.05, **P < 0.01, **P < 0.001, n.s: not significant (n = 3).

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