Table 1 Clinocopathologic characteristics of LUSC patients stratified by miR-375 expression.

From: MicroRNA-375 restrains the progression of lung squamous cell carcinoma by modulating the ERK pathway via UBE3A-mediated DUSP1 degradation

Characteristic

miR-375 expression

P

High

Low

n

42

47

 

T stage, n (%)

  

0.772

 T1

1 (1.6%)

1 (1.6%)

 

 T2

19 (31.1%)

14 (23%)

 

 T3

10 (16.4%)

10 (16.4%)

 

 T4

2 (3.3%)

4 (6.6%)

 

N stage, n (%)

  

0.544

 N0

24 (30.8%)

20 (25.6%)

 

 N1

12 (15.4%)

17 (21.8%)

 

 N2

2 (2.6%)

3 (3.8%)

 

M stage, n (%)

  

0.472

 M0

41 (46.1%)

47 (52.8%)

 

 M1

1 (1.1%)

0 (0%)

 

Pathologic stage, n (%)

  

<0.001

 I

3 (3.4%)

0 (0%)

 

 II

37 (41.6%)

26 (29.2%)

 

 III

2 (2.2%)

21 (23.6%)

 

Clinical stage, n (%)

  

0.421

 1

10 (16.4%)

6 (9.8%)

 

 2

14 (23%)

12 (19.7%)

 

 3

7 (11.5%)

11 (18%)

 

 4

1 (1.6%)

0 (0%)

 

Sex, n (%)

  

0.600

 Female

2 (2.2%)

1 (1.1%)

 

 Male

40 (44.9%)

46 (51.7%)

 

Age, mean ± SD

61.52 ± 9.04

63.55 ± 8.52

0.279

  1. Note: One patient was excluded due to technical failure during RNAScope procedure.
  2. Bold values indicates statistical significant P values (P < 0.05).
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