Fig. 4: The effects of FTO on AML cell chemotherapy resistance in vivo.
From: The role of m6A demethylase FTO in chemotherapy resistance mediating acute myeloid leukemia relapse
A Flow cytometry to detect the percentage of GFP+ cells in peripheral blood (PB) before Ara-C treatment. B Flow cytometry to detect the percentage of GFP+ cells in peripheral blood after Ara-C treatment. C Flow cytometry to detect the percentage of GFP+ cells in bone marrow after Ara-C treatment. D Representative images of tumor cell infiltration in spleen. The tumor cells were marked by white arrows. Scale bars represent 100 μm (upper panel) and 50 μm (lower panel), respectively, and the regions of lower panel were marked with white dotted line. P-values were calculated using Two-tailed Student’s t-test, and P < 0.05 was considered as statistically significant. ***P < 0.001 and ****P < 0.0001, ns: not significant.
