Fig. 4: NSUN2 induces migration and invasion of PC cells in vitro and facilitates metastasis in vivo.
From: NSUN2 stimulates tumor progression via enhancing TIAM2 mRNA stability in pancreatic cancer
A, B Migration ability and C, D invasion ability of PC cells with NSUN2 silence or overexpression were evaluated by Transwell assays. Data are shown as the mean ± SD of 3 replicates. *P < 0.05, **P < 0.01, ***P < 0.001. E, F Representative images of tumor peritoneal dissemination and statistical data were indicated. G, H Representative images of hematogenous metastasis model established by injecting PC cells through the tail vein. Scale bar = 100 μm. I, J Altered expression of EMT-associated genes in cells with NSUN2 silence or overexpression. Scale bar = 100 μm.
