Fig. 8: The clinical relevance and mechanism of NSUN2/TIAM2 axis in PC. | Cell Death Discovery

Fig. 8: The clinical relevance and mechanism of NSUN2/TIAM2 axis in PC.

From: NSUN2 stimulates tumor progression via enhancing TIAM2 mRNA stability in pancreatic cancer

Fig. 8: The clinical relevance and mechanism of NSUN2/TIAM2 axis in PC.The alternative text for this image may have been generated using AI.

A IHC staining of NSUN2 and TIAM2 in PC tissues and the positive correlation between them. (n = 31). Scale bar =100 μm. B Patients with high NSUN2 and high TIAM2 expression had poor overall survival. C The schematic figure shows that NSUN2 upregulates m5C level of TIAM2 mRNA, and may sustain the stability of TIAM2 mRNA; TIAM2 overexpression could promote cell proliferation, and activate EMT process in PC.

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