Fig. 1: There was more fatty infiltration in supraspinatus muscle than gastrocnemius muscle in tendon injury model. | Cell Death Discovery

Fig. 1: There was more fatty infiltration in supraspinatus muscle than gastrocnemius muscle in tendon injury model.

From: Suppressed Akt/GSK-3β/β-catenin signaling contributes to excessive adipogenesis of fibro-adipogenic progenitors after rotator cuff tears

Fig. 1

a Gross appearance of gastrocnemius and supraspinatus muscles six weeks after tendon injury or without tendon injury. AT-NC Achilles tendon-negative control, ATT Achilles tendon tear, RC-NC rotator cuff-negative control, RCT rotator cuff tear. Scale bar = 50 mm. b Measurement of triglycerides in gastrocnemius and supraspinatus muscles after tendon injuries (n = 5). c, d Oil red staining and statistical analysis for gastrocnemius and supraspinatus muscles after tendon injuries (n = 5). Scale bar = 100 µm. e, f Immunofluorescence staining and statistical analysis for gastrocnemius and supraspinatus muscles after tendon injuries (n = 5). Scale bar = 100 µm. g The relative mRNA expression of adipogenic-related genes in gastrocnemius and supraspinatus muscles after tendon injuries (n = 4). ** indicated p < 0.01, and *** indicated p < 0.001.

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