Fig. 3: RCT-FAPs showed higher adipogenic differentiation ability than ATT-FAPs. | Cell Death Discovery

Fig. 3: RCT-FAPs showed higher adipogenic differentiation ability than ATT-FAPs.

From: Suppressed Akt/GSK-3β/β-catenin signaling contributes to excessive adipogenesis of fibro-adipogenic progenitors after rotator cuff tears

Fig. 3: RCT-FAPs showed higher adipogenic differentiation ability than ATT-FAPs.

a, b The oil red staining and statistical analysis for ATT-FAPs and RCT-FAPs after 7-day adipogenic induction (n = 3). Scale bar = 100 µm. ATT-FAPs FAPs isolated from gastrocnemius muscle one week after tendon tears, RCT-FAPs FAPs isolated from supraspinatus muscle one week after tendon tears. c, d Immunofluorescence staining of perilipin1 and statistical analysis for ATT-FAPs and RCT-FAPs after 7-day adipogenic induction (n = 3). Scale bar = 50 µm. e Relative mRNA expression level of PLIN1, ADIPOQ, PPAR γ, FABP4, C/EBPα, and LPL for ATT-FAPs and RCT-FAPs after adipogenic induction (n = 3). *** indicated p < 0.001.

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