Fig. 4: YAP inactivation impaired prostate regeneration in vivo.
From: YAP is required for prostate development, regeneration, and prostate stem cell function
A Schematic figure showing the experimental strategy for prostate regeneration using YAP inhibitor Verteporfin (VP). B Overview of the prostates after regeneration at different time periods. n = 3 for each group, Scale bar 2 mm. C Hematoxylin & Eosin staining of ventral prostate sections at indicated regeneration stages. D Histologic examination of ventral prostate sections under oil lens after 14 days of regeneration. E, F The nucleus/cytoplasm ratio and luminal cell height of ventral prostates epithelial after 14 days of regeneration were quantified. Bar graph expresses mean ± SEM from three pairs of mice, five sections per prostate, P < 0.05. VP verteporfin.
