Fig. 3: Alterations of the MMR system in the breast cancer patient. | Cell Death Discovery

Fig. 3: Alterations of the MMR system in the breast cancer patient.

From: A primary luminal/HER2 negative breast cancer patient with mismatch repair deficiency

Fig. 3: Alterations of the MMR system in the breast cancer patient.

A MSH2, MSH6 and PMS2 genomic alterations in the METABRIC dataset. Samples were clustered based on their molecular subtype. Data were obtained from cBioPortal. B Schematic structural features of the MSH2 protein. Patient’s mutation is indicated by an arrow. Data were obtained from cBioPortal. C Schematic structural representation of the PMS2 protein. Patient’s mutation is indicated by an arrow. Data were obtained from cBioPortal.

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