Table 1 Cancer devitalization using high hydrostatic pressure.

From: Establishing safe high hydrostatic pressure devitalization thresholds for autologous head and neck cancer vaccination and reconstruction

Authors

Pressure amplitude [MPa]

Complete devitalization [MPa]

Time [min]

Cancer

Remaining viable cells

Rückert et al. [25]

200

N/A

5

Melanoma,

mammary

N/A

Seitz et al. [10]

100–500

300

10–15

Melanoma, colon

None

Urbanova et al. [20]

150–350

200

10–15

Prostate, ovary,

lung

None

Hradilova et al. [22]

250

250

10

Lung

N/A

Mikyskova et al. [21]

200

N/A

10

Lung,

prostate

<10%

Chen et al. [26]

0.01–0.1

N/A

>60

Urothelial

75 × 104

Fucikova et al. [23]

150–350

250

10

Leukemia, ovary

prostate

N/A

Weiss et al. [4]

100–500

300

5

Melanoma, colon,

lymphoma

“Few viable cells”'

Schauwecker et al. [27]

150–300

300

10

Chondrosarcoma,

ostesarcoma

None

Eisenthal et al. [7]

60–120

N/A

15

Melanoma

N/A