Fig. 4: HOXA5 expression is correlated with stem-like properties in PCa. | Cell Death Discovery

Fig. 4: HOXA5 expression is correlated with stem-like properties in PCa.

From: TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signaling

Fig. 4: HOXA5 expression is correlated with stem-like properties in PCa.

A Representative images of sphere formation and corresponding quantitative results. B Flow cytometry assay with CD133 in PCa cell lines and quantitative results. C Circos plot displaying the interconnectivity between HOXA5 and stemness-related markers. D The protein expression of cancer stem cell markers including Nanog, Sox-2, Oct4, and CD44 in PCa cells. *P < 0.05, **P < 0.01. Results were presented as mean ± SD.

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