Fig. 3: CoCl2 decreases Hippo pathway under high cell density conditions.
From: YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions
A MDCK cells at low and high density were treated with or without 400 μM CoCl2 for 8 h. Protein levels of Hippo pathway in each group were determined by Western blotting. The quantification of (B) phospho-MST1/MST1, (C) phospho-LATS1/LATS1, and (D) phospho-YAP/YAP were presented as mean ± SEM. *p < 0.05 and **p < 0.01 vs. control group in low-cell density conditions. #p < 0.05 and ##p < 0.01 vs. control group in high-cell density conditions.
