Fig. 7: The RPLP2/HIF-1α axis modulates glycolysis and tumour proliferation in mice. | Cell Death Discovery

Fig. 7: The RPLP2/HIF-1α axis modulates glycolysis and tumour proliferation in mice.

From: RPLP2 activates TLR4 in an autocrine manner and promotes HIF-1α-induced metabolic reprogramming in hepatocellular carcinoma

Fig. 7

A Cells were subcutaneously injected into the flanks of BALB/c nude mice to investigate proliferative ability. Images of the dissected tumours from the BALB/c nude mice (n = 6). B The tumour growth curves of each group are shown (n = 6, mean ± SD). C The tumour weight of each group is shown (n = 6, mean ± SD). D, E IHC staining of xenograft tumour sections with the indicated treatment and quantitative analysis (n = 6, mean ± SD). The scale bars represent 100 μm. *P < 0.05 versus corresponding control; ns means nonsignificant.

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