Fig. 4: RNA sequencing results of AGS cells treated with CEP. | Cell Death Discovery

Fig. 4: RNA sequencing results of AGS cells treated with CEP.

From: Cepharanthine, a regulator of keap1-Nrf2, inhibits gastric cancer growth through oxidative stress and energy metabolism pathway

Fig. 4

A AGS cells were treated with 15 μmol/L CEP for 48 h. The RNA sequencing volcanic map revealed significant differentially expressed genes. The screening criteria for differential genes are |log2 Fold change| ≥ 1 and q < 0.05. Up for 1523; down for 2162. B The RNA sequencing heat map indicated significant differentially expressed genes. Red indicates high gene expression, while blue indicates low gene expression. The abscissa represents the sample clustering, and the ordinate represents the gene clustering. C GO annotation analysis of AGS cells treated with CEP compared to the control group. D KEGG pathway enrichment analysis of AGS cells treated with CEP revealed that different colors represented different enrichment levels, with the redder color representing more significant enrichment.

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