Fig. 8: Schematic model summarising alterations in the expression of the indicated ferroptosis hallmarks in MUM samples after 1,4-dihydroxy quininib treatment. | Cell Death Discovery

Fig. 8: Schematic model summarising alterations in the expression of the indicated ferroptosis hallmarks in MUM samples after 1,4-dihydroxy quininib treatment.

From: 1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature

Fig. 8

A Figure showing the specific factors modulated by 1,4-dihydroxy quininib in a time-dependent fashion. Created with BioRender.com. Subscription: Institution (University College Dublin) B. Table summarising the significant differences in ferroptosis hallmarks after 1,4-dihydroxy quininib. HO-1 and GCLM upregulations are based on OMM2.5 cells proteome profiling results. Non-significant differences are represented with “=”, significant downregulation with “↓” and significant upregulation with “↑”. Q7 = 1,4-dihydroxy quininib; Pi = phosphorylated; HMOX = HO-1; h = hours.

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