Fig. 1: Early activation of FUNDC1 protected against SCI and promote the repair process. | Cell Death Discovery

Fig. 1: Early activation of FUNDC1 protected against SCI and promote the repair process.

From: FUNDC1-induced mitophagy protects spinal cord neurons against ischemic injury

Fig. 1

A The schematic diagram for local injection of AAV-Fundc1 virus into the spinal cord. B BBB scores at various times following spinal cord contusions in each group of rats (mean ± SD, n = 3). C Example footprints of rats walking 1 week following SCI (n = 3). Red: paw print—hind paw. D Representative cross-sectional H&E staining of the spinal cord for each group (n = 3). Scale bar = 1000 μm or 200 μm. E, F Nissl staining was performed to quantify the number of surviving neurons under each field of view in each group (mean ± SD, n = 3). Scale bar = 250 μm. Two-way ANOVA was used to compare the groups. ****p < 0.0001, **p < 0.01, and *p < 0.05.

Back to article page