Fig. 5: Cancer-associated fibroblasts-derived SULF1 promoted the CDDP resistance of GC cells. | Cell Death Discovery

Fig. 5: Cancer-associated fibroblasts-derived SULF1 promoted the CDDP resistance of GC cells.

From: Cancer associated fibroblasts-derived SULF1 promotes gastric cancer metastasis and CDDP resistance through the TGFBR3-mediated TGF-β signaling pathway

Fig. 5

A Western blotting to detected the expression of SMAD2, SMAD3, p-SMAD2 and p-SMAD3 in CDDP treated HGC27 (8 μm; 24 h) and AGS (2 μm; 24 h) cells from indicated groups. B CCK8 assay to detected the cell viability of CDDP treated HGC27 cells from indicated groups. C Quantitative analysis results of IC50 of HGC27 cells regarding CDDP using CCK8 assay results. D CCK8 assay to detected the cell viability of CDDP treated AGS cells from indicated groups. E Quantitative analysis results of IC50 of AGS cells regarding CDDP using CCK8 assay results. Representative images (F) and quantitative analysis results (G) of colony formation assay in CDDP treated HGC27 (8 μm; 24 h) and AGS (2 μm; 24 h) cells from indicated groups. Representative images (H) and quantitative analysis results (I) of flow cytometry in CDDP treated HGC27 (8 μm; 24 h) and AGS (2 μm; 24 h) cells from indicated groups.

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