Fig. 6: TGF-β pathway was involved in SULF1-induced malignant phenotype of GC cells. | Cell Death Discovery

Fig. 6: TGF-β pathway was involved in SULF1-induced malignant phenotype of GC cells.

From: Cancer associated fibroblasts-derived SULF1 promotes gastric cancer metastasis and CDDP resistance through the TGFBR3-mediated TGF-β signaling pathway

Fig. 6

A Western blotting to detected the expression of EMT markers in HGC27 and AGS cells from indicated groups with or without treated with TGF-β1 (20 μg/mL) for 24 h. B Quantitative analysis results of wound-healing assays in HGC27 and AGS cells from indicated groups with or without treated with TGF-β1 (20 μg/mL) for 24 h. C Representative images of wound-healing assays in HGC27 cells from indicated groups with or without treated with TGF-β1 (20 μg/mL) for 24 h. D Representative images of transwell assays in HGC27 cells from indicated groups with or without treated with TGF-β1 (20 μg/mL) for 24 h. Quantitative analysis results of transwell assays in HGC27 (E) and AGS (F) cells from indicated groups with or without treated with TGF-β1 (20 μg/mL) for 24 h. Representative images (G) and quantitative analysis results (H) of colony formation assay in CDDP treated HGC27 (8 μm; 24 h) and AGS (2 μm; 24 h) cells from indicated groups with or without treated with TGF-β1 (20 μg/mL) for 24 h. Representative images (I) and quantitative analysis results (J) of flow cytometry in CDDP treated HGC27 (8 μm; 24 h) and AGS (2 μm; 24 h) cells from indicated groups with or without treated with TGF-β1 (20 μg/mL) for 24 h.

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