Fig. 3: Signaling pathways of the Tspan protein family regulating tumor cell proliferation.
From: Tspan protein family: focusing on the occurrence, progression, and treatment of cancer

The Tspan protein family has a dual role in cancer proliferation. Tspan1, Tspan15, Tspan27, and Tspan31 promote cancer proliferation, and conversely, Tspan7 and Tspan29 inhibit cancer proliferation.