Table 3 Demographic characteristics of 36 organ donors and recipients included in the study.

From: Detection of inflammasome activation in liver tissue during the donation process as potential biomarker for liver transplantation

Variables

Donors (n = 36)

P

Recipients (n = 36)

DBD (n = 23)

DCD (n = 13)

Age

55.30 ± 14.65; 54 (25-77)

57.85 ± 13.58; 62 (26-76)

0.611a

60.97 ± 6.13; 61 (48-73)

Sex

  Male

12 (52.2)

10 (76.9)

0.134b

28 (77.8)

  Female

11 (47.8)

3 (23.1)

 

8 (22.2)

 BMI

27.02 ± 3.98; 26.65 (19.23-37.04)

25.15 ± 4.35; 24.69 (18.41-34.60)

0.203a

26.87 ± 4.77; 26.77 (19.82-37.34)

 CIT (min)

284.90 ± 174.80; 245 (30-560)

244.60 ± 66.06; 240 (180-395)

0.349a

 

Cause of death

  CVA

12 (52.2)

5 (38.5)

0.117b

 

  TBI

7 (30.4)

1 (7.7)

  

  Anoxic encephalopathy

2 (8.7)

2 (15.4)

  

  Cardiomyopathy

0

2 (15.4)

  

  Other

2 (8.7)

3 (23.1)

  

Pre-donation LFTs

  AST (U/L)

79.1 ± 116; 32 (11-442)

59.5 ± 69.4; 28 (10-260)

0.584a

 

  ALT (U/L)

53.7 ± 76.4; 21.5 (8-270)

57.8 ± 64.5; 37 (8-202)

0.874a

 

  PTp activity (%)

82.8 ± 23.7; 89.5 (14-126)

80.6 ± 24; 76.5 (34-129)

0.795a

 

 NRP

 

11 (84.6)

  

 Functional WIT (min)

 

13.50 ± 6.49; 14 (2-25)

  

 Diseases

    

  Alcoholic cirrhosis

   

20 (55.6)

  HCV

   

4 (11.1)

  Ischemic cholangiopathy

   

3 (8.3)

  Cryptogenic liver Cirrhosis

   

2 (5.6)

  NASH

   

2 (5.6)

  Other

   

5 (13.8)

 Re-transplant patients

   

4 (11.1)

 Intraoperative death

   

1 (2.8)

  1. Continuous variables are expressed as mean ± SD; median (range). Qualitative variables are expressed as frequency (%). DBD donation after brain death, DCD donation after circulatory death, BMI body mass index, CIT cold ischemia time, CVA acute cerebrovascular accident, TBI traumatic brain injury, LFTs liver function tests, AST aspartate aminotransferase, ALT alanine aminotransferase, PTp percentage of prothrombin time, NRP normothermic regional perfusion, WIT warm ischemia time, HCV hepatitis C virus, HBV hepatitis B virus, NASH non-alcoholic steohepatitis. aT-test. bChi-square test.