Fig. 3: GLUT1 differentially localizes to the cell membrane and Golgi in HNSCC cell lines. | Cell Death Discovery

Fig. 3: GLUT1 differentially localizes to the cell membrane and Golgi in HNSCC cell lines.

From: GLUT1 inhibitor BAY-876 induces apoptosis and enhances anti-cancer effects of bitter receptor agonists in head and neck squamous carcinoma cells

Fig. 3

GLUT1 (Cell Signaling mAB #71831 or mAB #12939)and A Na+/K+-ATPase pump (cell membrane; Abcam #ab76030), B GM130 (Golgi apparatus; BD Transduction Laboratories #610822), C mitotracker (mitochondria; Thermo Fisher #M22425), or D LAMP1 (lysosome; Abcam #ab24170) expression in SCC47. GLUT1 and E Na+/K+-ATPase pump (cell membrane; Abcam #ab76030) or F GM130 (Golgi apparatus; BD Transduction Laboratories #610822) expression in RPMI2650 cells via immunofluorescence with DAPI (cyan, nucleus) and phalloidin (green, actin) markers. Scale bars = 30 μm. Images best represent phenotype observed in n > 12 separate cultures.

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