Fig. 7: Over-expression of NSF effectively mitigated ischemic neuronal injury.

Compared with those in OGD +Lv-ctrl group, the improved cell viability (D), promoted the number of Nissl bodies (A, B) and decreased FJC-positive cells (A, C) were detected in OGD + NSF group. This suggests that cellular protection against ischemia was induced by NSF over-expression. The yellow arrows indicated viable neurons, and the red arrows showed pyknotic neurons. n = 6, *p < 0.05, **p < 0.01, ***p < 0.001, ns indicates that the data are not statistically different.