Fig. 6: NS protects H9C2 cells from H/R injury by promoting autophagy. | Cell Death Discovery

Fig. 6: NS protects H9C2 cells from H/R injury by promoting autophagy.

From: Myocardial ischemia-reperfusion injury upregulates nucleostemin expression via HIF-1α and c-Jun pathways and alleviates apoptosis by promoting autophagy

Fig. 6: NS protects H9C2 cells from H/R injury by promoting autophagy.The alternative text for this image may have been generated using AI.

A Autophagy-related pathway was enriched after H/R injury using GSEA. B Representative images of flow cytometry analysis depict the apoptosis rates in the indicated groups. C–F Autophagy-related proteins, Beclin1, p62, LC3I, and LC3II, were detected by western blot analysis after interfering with NS and H/R. G, H NS and LC3 were detected by immunofluorescence after interfering with NS and H/R and quantified. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, vs. 6 h group.

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