Fig. 3: PDLIM1 overexpression promoted GBM progression. | Cell Death Discovery

Fig. 3: PDLIM1 overexpression promoted GBM progression.

From: Identification of PDLIM1 as a glioblastoma stem cell marker driving tumorigenesis and chemoresistance

Fig. 3

The overexpression of PDLIM1 in U87 cells was validated by A RT-qPCR and B, C western blots. The overexpression of PDLIM1 in A172 cells was validated by D RT-qPCR and E, F western blots. MTT assays showing that PDLIM1 overexpression promoted cell growth in both G U87 and H A172 cells, respectively. Immunostaining against Ki67 was performed on control and PDLIM1-overexpressing I, J U87 and K, L A172 cells, respectively. Annexin V/PI apoptosis assays were performed on control and PDLIM1-overexpressing M, O U87 and N, P A172 cells, respectively. Control, empty vector control; PDLIM1-OE, PDLIM1 overexpression; *P < 0.05.

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