Fig. 5: PDLIM1 overexpression promoted tumorigenesis in xenograft mice.

Control and PDLIM1-overexpressing U87 cells were subcutaneously injected into BALB/c Nude Mice, respectively. Tumor growth was continuously monitored for 4 weeks. A The mice of both groups at sacrifice. B The tumors of both groups at sacrifice. C The weight of tumors in both groups. D The tumor volumes of both groups. E, F The immunohistochemistry staining against Ki67 on the tumor section slides of both groups. Control, empty vector control; PDLIM1-OE, PDLIM1 overexpression; *P < 0.05.