Fig. 1: NEDD4L expression is low and serves as a good prognosis marker in ESCC. | Cell Death Discovery

Fig. 1: NEDD4L expression is low and serves as a good prognosis marker in ESCC.

From: NEDD4L contributes to ferroptosis and cell growth inhibition in esophageal squamous cell carcinoma by facilitating xCT ubiquitination

Fig. 1: NEDD4L expression is low and serves as a good prognosis marker in ESCC.

A NEDD4L protein expression was decreased in ESCC tissues (n = 25) compared with normal tissue (n = 25) as analyzed by IHC. Scale bars, 100 μm. B Representative images of NEDD4L low expression (n = 62) and high expression (n = 80) analyzed by IHC. Scale bars, 100 μm. C NEDD4L expression score in 142 cases of ESCC (n = 142). D Overall survival analysis revealed that higher expression of NEDD4L was related with poorer overall survival of ESCC patients (n = 142). p <0.01, log-rank test.

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