Fig. 3: Intratumoral bacteria and possible immune regulation of mast cell in digestive system tumors.
From: Mast cells: key players in digestive system tumors and their interactions with immune cells
This figure illustrates the complex interaction mechanisms between intratumoral bacteria, immune cells, and mast cells in pancreatic cancer, colorectal cancer, and gastric cancer. Intratumoral bacteria regulate immune cell activity and mast cell function through direct interactions or the secretion of metabolic products, thereby influencing the tumor immune microenvironment and tumor progression. In the figure, question marks represent potential connections that remain unexplored but are hypothesized to exist.
