Fig. 3: H. pylori induces differential m6A modification in GC cells. | Cell Death Discovery

Fig. 3: H. pylori induces differential m6A modification in GC cells.

From: Helicobacter pylori reduces METTL14-mediated VAMP3 m6A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling

Fig. 3

a Volcano plots were constructed to determine the m6A modification levels of differentially expressed m6A-modified genes at *p < 0.05 in AGS cells treated with Hp26695 at MOI = 100 for 12 h; blue indicates genes with downregulated m6A modification, and red indicates genes with upregulated m6A modification. b m6A consensus motifs with the lowest p values detected by DREME. c Proportions of m6A peak distribution in the 5′UTR, CDS and 3′UTR regions of mRNA transcripts. d KEGG pathway analysis of m6A peak-downregulated genes in AGS cells treated with Hp26695 compared with the control. *p < 0.05, **p < 0.01, ***p < 0.001.

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