Fig. 5: Drg2 does not affect the expression of RANKL (Tnfsf11) and osteoprotegerin (OPG, Tnfrsf11b). | Cell Death Discovery

Fig. 5: Drg2 does not affect the expression of RANKL (Tnfsf11) and osteoprotegerin (OPG, Tnfrsf11b).

From: Rac1-dependent regulation of osteoclast and osteoblast differentiation by developmentally regulated GTP-binding 2

Fig. 5

A Control siRNA or Drg2 siRNA-transfected osteoprogenitor cells were cultured in vitamin D3 (Vit.D3) for 2 days. The mRNA levels were analyzed using quantitative PCR. N = 3. B Control siRNA or Drg2 siRNA-transfected osteoprogenitor cells were co-cultured with BMMs in the presence or absence of vitamin D3 (Vit.D3) or prostaglandin E2 (PGE2) for 6 days. The numbers of osteoclasts were determined after TRAP staining. N = 3. Scale bar, 200 µm.

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