Fig. 1: LINC02418 is overexpressed in colorectal carcinoma and correlates with poor clinical outcomes. | Cell Death Discovery

Fig. 1: LINC02418 is overexpressed in colorectal carcinoma and correlates with poor clinical outcomes.

From: m6A-modified LINC02418 induces transcriptional and post-transcriptional modification of CTNNB1 via interacting with YBX1 and IGF2BP1 in colorectal cancer

Fig. 1: LINC02418 is overexpressed in colorectal carcinoma and correlates with poor clinical outcomes.

A Venn diagram of highly expressed lncRNAs in CRC tissues of the three GEO datasets (GSE102340, GSE83889 and GSE81558) revealed the cancer-promoting lncRNA, LINC02418. (B) Expression of LINC02418 in CRC and non-tumor tissues in the TCGA dataset. C–D Expression of LINC02418 in CRC and nontumor tissues in the GSE87211 and GSE106582 datasets. E High LINC02418 levels predict worse PFS based on the TCGA dataset. F The expression levels of LINC02418 were assessed in 10 pairs of clinical colorectal cancer (CRC) samples and their corresponding adjacent tissues using qPCR assay. G A qPCR analysis was employed to quantify the protein expression levels of LINC02418 in human colorectal cancer (CRC) cell lines, as well as the normal colon cell line CCD-18Co. H The subcellular localization of LINC02418 (red) in RKO was measured by RNA FISH (Scale bar, 30μm). I Quantification of LINC02418 distribution percentage was measured by nucleocytoplasmic fractionation.

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