Fig. 5: Mesenchymal stem cell co-culture increases migration ability, inhibited by Capsanthin. | Cell Death Discovery

Fig. 5: Mesenchymal stem cell co-culture increases migration ability, inhibited by Capsanthin.

From: Capsanthin inhibits migration and reduces N-linked glycosylation of PD-L1 via the EZH2-PD-L1 axis in triple-negative breast cancer brain metastasis

Fig. 5

A Co-culturing mesenchymal stem cells (3A6) with MDA-MB-231 breast cancer cells significantly increases the migration ability of 3A6 cells. Capsanthin treatment (10 μM) effectively inhibits this enhanced migration at 24 h. Student’s t-test (n = 3). B Co-culturing 3A6 cells with the brain metastatic breast cancer cell line 231Br increases the migration of 3A6 cells, which is significantly reduced by Capsanthin treatment (10 μM) at 24 h. Student’s t-test (n = 3). (*p < 0.05, **p < 0.01).

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