Fig. 7: COL6A1 promoted the migration and invasion of primary EVTs through the APJ/AKT/mTOR pathway. | Cell Death Discovery

Fig. 7: COL6A1 promoted the migration and invasion of primary EVTs through the APJ/AKT/mTOR pathway.

From: Insufficient expression of COL6A1 promotes the development of early-onset severe preeclampsia by inhibiting the APJ/AKT signaling pathway

Fig. 7: COL6A1 promoted the migration and invasion of primary EVTs through the APJ/AKT/mTOR pathway.

A, B Transwell assays were conducted to detect the effect of COL6A1 on the migration and invasion abilities of primary EVTs (100×, scale bar: 100 μm). C, D Primary EVTs were firstly transfected with pcDNA3.1 or COL6A1, and ML221 was added alone or in combination with SC79 for 24 h. Transwell assays were performed to measure changes in migration and invasion (100×, scale bar: 100 μm) (data are mean ± SD, **P < 0.01, ***P < 0.001, n = 3).

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