Fig. 6: Analysis of cell cycle dynamics in CRC and glioma cell lines after 72 h of treatment.

A Representative dot plots illustrating cell cycle frequencies of SW480 and COLO-320 cell lines after 72 h of treatment with and without 200 nM rotenone or 200 nM antimycin A, analyzed using BrdU/PI staining. B Representative dot plots depicting cell cycle frequencies of LN428 and D247MG cell lines after 72 hs of treatment with and without 20 μM temozolomide or 20 μM carmustine, analyzed using BrdU/PI staining. C Distribution of cells in G1, S, and G2 phases in control and treated CRC and glioma cell lines after 72 h of treatment. D Changes in the proportion of cells in G1 and G2 phases for SW480 and COLO-320 cell lines after treatment with 200 nM rotenone or 200 nM antimycin A, relative to untreated cells. E Changes in the proportion of cells in G1 and G2 phases for LN428 and D247MG cell lines after treatment with 20 μM temozolomide or 20 μM carmustine, relative to untreated cells. All values are means ± SEM; “ns” indicates non-significant; *p < 0.05, **p < 0.01 and ***p < 0.001; n = 3.