Fig. 7: Expression of ROS and apoptotic marker in DZN exposed testicular cells (GC-1 spg, TM3, and TM4). | Cell Death Discovery

Fig. 7: Expression of ROS and apoptotic marker in DZN exposed testicular cells (GC-1 spg, TM3, and TM4).

From: Diazinon induces testicular dysfunction and testicular cell damage through increased reactive oxygen species production in mouse

Fig. 7

A Sod1, Sod2, Cat, Gpx, Ho-1, Nrf2, and Nqo1 expression in GC1-spg cells treated with 300 µM DZN for 24 h. Values on graph are presented as the mean ± SD (log2 scale) (n = 5). B Protein expression levels of Bad, Cleaved-caspase 3, Caspase 3, Phospho-p53, P53, and HO-1 in GC1-spg cells exposed to 0–300 µM DZN. C Graph shows relative protein levels (mean ± SD, n = 5). D Sod1, Sod2, Cat, Gpx, Ho-1, Nrf2, and Nqo1 expression in TM3 cells before and after exposure to 300 µM DZN. Values on graph are presented as the mean ± SD (log2 scale). E Protein expression levels of Bad, Cleaved-caspase 3, Caspase 3, Phospho-p53, P53, and HO-1 in TM3 cells exposed to 0–300 µM DZN. F Graph shows relative protein levels (mean ± SD, n = 5). G Sod1, Sod2, Cat, Gpx, Ho-1, Nrf2, and Nqo1 expression in TM4 cells before and after exposure to DZN. Values on graph are presented as the mean ± SD (log2 scale). H Protein expression levels of Bad, Cleaved-caspase 3, Caspase 3, Phospho-p53, P53 and HO-1 in TM4 cells exposed to 0, 100, 200 and 300 µM DZN. I Graph shows relative protein levels (mean ± SD, n = 5). Asterisks indicate significant differences between the treatment and control groups at *p < 0.05, ** p < 0.01, and ***p < 0.001.

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