Fig. 3: Future co-culture models.
From: Tumor organoid-immune co-culture models: exploring a new perspective of tumor immunity
The figure depicts a possible future where in vitro co-culture more closely mimics the in vivo tumor microenvironment. Co-culture of organoids and immune cells can avoid the limitations of tumor organoid models and explore how cell-to-cell crosstalk affects immune responses. The top left figure is adapted from ref. [77], BioMed Central Limited. The top right figure is adapted from ref. [38], Nature Publishing Group Limited. The bottom right figure is adapted from ref. [61], National Academy of Sciences Limited. The bottom figure is adapted from ref. [68], Rockefeller University Press Limited. The middle left figure is adapted from ref. [81], Frontiers Media S.A. Limited. The surrounding experimental figures do not represent the actual situation of this model.
