Table 1 The modification sites and Kinases/Phosphatases.

From: DRP1, fission and apoptosis

Domain

Range

Sites

Kinase/Phosphatase

GTP

21–299

Ser40/44

GSK3β [70]

Thr266

c-Abl [72]

MD

300–491

Thr368/449

c-Abl [72]

VD

499-637

Ser579

CDK5 [57, 58]

Ser585

CDK [56]

Ser600

ROCK1 [67]

Ser616

PINK1 [49, 50];CDK19/Cdk8 [51]; CDK5 [53,54,55]; TBK1 [59];

TGF-β [60];STAT2 [61];δPKC [62, 127,128,129];

MAPK1 [63];CaMKII [64, 65];JNK [130]; ERK1/2 [63, 131,132,133,134];ROCK [67]

Ser622

CaMKIIa [66]

Ser637

AMPK [68];PKA [108, 135,136,137,138];CaMKIα [139];PKD [140];CaN [97, 141, 142]; ROCK1 [74];PP1/PP2A [73,74,75];PGAM5 [77]; AKAP1 [78];

GED

640–734

Ser656

ROCK1 [76]

Ser693

GSK3β [71]

  1. Sites: underlined sites driving fission if phosphorylated; italicized sites driving fusion if phosphorylated.
  2. Kinases/Phosphatases: underlined ones are kinases; italicized ones are phosphatases.
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