Fig. 2: Simulated structure of USP6. | Cell Death Discovery

Fig. 2: Simulated structure of USP6.

From: Physiological roles and therapeutic implications of USP6

Fig. 2

A USP6 Domains and Isoforms USP6 comprised of 2 domains: USP domain and a Rap-GAP homology/TBC domain. The short isoform of USP6 is lacking histidine residue and thus has a non-functional USP domain. B Graphical presentation of secondary structure of protein obtained by AlphaFold 2, blue color indicating USP domain while green color representing the TBC domain. C The structure of full length human USP6 predicted by PSIPRED server, where Gray color show (>90 pLDDT), Pink (pLDDT > 70), and yellow (pLDDT > 50).

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