Fig. 1: Structure of ANXA2.
From: ANXA2 in cancer: aberrant regulation of tumour cell apoptosis and its immune interactions
C represents the cysteine residue at position 8, S represents the serine residues at positions 11 and 25, and Y represents the tyrosine residue at position 23. The amino-terminal (N-terminal) contains the S100A10 (p11) binding site and a nuclear export signal (NES). The carboxy-terminal (C-terminal) includes four repeated amino acid sequences.
